Since 2017 the Guardians and White Sox have met 157 times in the regular season, with the Guardians holding a 94–63 edge in the series.
Most recently the Guardians won 6–3 on September 16, 2026.
Right now the Guardians are 85–77 and the White Sox are 84–78, with the Guardians at 11 days since a win against the White Sox's 2.
| Season | Wins |
|---|---|
| 2026 | Guardians 6, White Sox 7 |
| 2025 | Guardians 11, White Sox 2 |
| 2024 | Guardians 8, White Sox 5 |
| 2023 | Guardians 5, White Sox 8 |
| 2022 | Guardians 12, White Sox 7 |
| 2021 | Guardians 9, White Sox 10 |
| 2020 | Guardians 8, White Sox 2 |
| 2019 | Guardians 8, White Sox 11 |
| 2018 | Guardians 14, White Sox 5 |
| 2017 | Guardians 13, White Sox 6 |
| Date | Host | Winner | Score |
|---|---|---|---|
| Wed, Sep 16 2026 | Guardians home | Guardians | 6–3 |
| Tue, Sep 15 2026 | Guardians home | Guardians | 7–6 |
| Mon, Sep 14 2026 | Guardians home | White Sox | 7–3 |
| Sun, Aug 9 2026 | White Sox home | White Sox | 5–3 |
| Sat, Aug 8 2026 | White Sox home | White Sox | 6–3 |
| Fri, Aug 7 2026 | White Sox home | Guardians | 8–2 |
| Sun, Jul 5 2026 | Guardians home | White Sox | 7–6 |
| Sat, Jul 4 2026 | Guardians home | White Sox | 3–1 |
| Fri, Jul 3 2026 | Guardians home | Guardians | 4–3 |
| Thu, Jul 2 2026 | Guardians home | Guardians | 6–5 |
| Wed, Jun 24 2026 | White Sox home | Guardians | 4–3 |
| Tue, Jun 23 2026 | White Sox home | White Sox | 2–1 |
| Mon, Jun 22 2026 | White Sox home | White Sox | 6–5 |
| Sun, Sep 14 2025 | Guardians home | Guardians | 3–2 |
| Sat, Sep 13 2025 | Guardians home | Guardians | 3–1 |
Full schedules and drought counters: Cleveland Guardians and Chicago White Sox.
White Sox vs Tigers, White Sox vs Royals, White Sox vs Twins, Guardians vs Tigers, Guardians vs Royals, Guardians vs Twins, Tigers vs Royals, Tigers vs Twins, Royals vs Twins.